Tottenham will welcome back a raft of first-team regulars, having made eight changes for the FA Cup win at Tranmere.
Eric Dier is still out following appendix surgery and Lucas Moura is an injury doubt, but Mousa Dembele and Jan Vertonghen are back in training.
Paul Pogba is set to be available for Manchester United after he missed the FA Cup third round with a leg problem.
Eric Bailly remains suspended, while Chris Smalling could miss a seventh straight game because of a foot injury.
Marcos Rojo has returned to Argentina to continue his rehabilitation.
One of these two managers Solkskjaer and Pochettino definitely wants to be the next permanent Manchester United boss, the other is saying nothing.
There’s no question that when United appointed Ole Gunnar Solskjaer they had chosen their moment carefully: four supremely winnable games lay ahead, and United have duly won them.
But Solskjaer has done more than just win – it’s the way United have played and the sight of a couple of youngsters being given their chance. Solskjaer can really do no more.
Mauricio Pochettino’s credentials are beyond question. Spurs are certainly London’s top side just now, and have achieved that without spending in the summer and without a working stadium to call their own.
Chairman Daniel Levy will understand that, if they are to keep the popular Argentine, then both the new stadium and Levy’s wallet had better be open soon.